CASE 3

Kindly provided by James Cartwright of Edinburgh Veterinary School.

Clinical history

A 17 year old, male neutered, Arab cross horse (Equus callabus) presented with a 2 month history of mild but progressive anorexia accompanied by weight loss and chronic, intermittent diarrhoea.  Mild elevations in ALP and GGT were present; total bilirubin and fasting serum bile acids were within normal limits.

At necropsy, gross abnormalities were restricted to the liver (fig. 1) and left lung (fig. 2).

Describe the gross findings.

Give a morphological diagnosis.

Name the aetiological agent.

What are the lesions within these visceral organs?  Outline their major gross and histopathological features.

Is this condition clinically significant in the horse?

Is the aetiological agent a health risk to humans?

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