The 36th Annual Scientific Meeting of the BSTP and AGM
Pathology of Humanised Mouse Models
Thursday 11th and Friday 12th November 2021
Date and venue to be confirmed
Immunodeficient mice reconstituted with a human immune system are increasingly used for modelling the human immune compartment in numerous preclinical applications, such as adoptive cell therapy and immuno-oncology studies. With the advent of new Advanced Therapy Medicinal Products, humanised mice are a key component of efficacy and safety assessment in preclinical programmes, including GLP studies. However, limited information is available concerning the morphological aspects of human cell engraftment and the spectrum of spontaneous and experimentally induced histopathological lesions occurring in these mice.
Working with the Pathological Society of Great Britain and Ireland the meeting will cover the main features of the different humanised mouse platforms; their experimental applications in drug development, oncology and gene and cell therapies; specific safety and regulatory considerations; and future promise and remaining challenges. A short session will be also devoted to chimeric mice with humanised livers, as tools for the study of human drug metabolism and toxicity. The aim is also to have parallel sessions covering ‘mouse pathology’ and ‘humanised mice in preclinical studies: context and regulatory aspects’.
The first day of the meeting will include the Annual General Meeting of the BSTP.
Keep checking the website for details of bursaries and the submission of abstracts for case presentations.
Sponsorship and Promotional Opportunities
We feel that by participating in this conference it would allow your company to showcase a range of products to a diverse group of scientists. Please contact the BSTP at firstname.lastname@example.org more information.
CLICK HERE for more information.